KMID : 1035620170050050280
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Allergy Asthma & Respiratory Disease 2017 Volume.5 No. 5 p.280 ~ p.286
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Efficacy of early steroid use in Mycoplasma pneumoniae pneumonia
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Kim Hee-Seong
Song Myung-Gon Kim Yong-Wook Kim Kyoung-Sim Kim Eun-Young Kim Young Jang Hae-In Cho Hyoung-Min
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Abstract
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Purpose: The aim of this study was to evaluate whether or not the early use of steroid is useful for treating Mycoplasma pneumoniae pneumonia.
Methods: A prospective study was conducted on 85 patients with M. pneumoniae pneumonia admitted to Gwangju Christian Hospital between September 2015 and April 2016. A total of 85 patients were enrolled. Of these, 33 were treated with steroids (methyl-prednisolone 1 mg/kg/day), while 52 were not; both were treated with macrolides. The overall duration of fever was compared between the 2 groups and findings on chest radiographs were evaluated for their deterioration.
Results: The duration of fever after admission (1.36¡¾0.92 days vs. 2.17¡¾1.30 days, P=0.003) and the overall duration of fever (4.42¡¾2.13 days vs. 6.07¡¾2.59 days, P=0.003) were significantly lower in the steroid group. The duration of fever before admission was not different between the steroid and macrolide groups (3.06¡¾1.74 days vs. 3.90¡¾2.21 days, P=0.068). On chest radiographs taken 3 days later, 1 of 33 patients in the steroid group and 5 of 50 patients in the macrolide group worsened, although there was no statistically significant difference between the 2 groups (P=0.395). There was no significant difference in the duration of hospitalization between the 2 groups (6.72¡¾1.54 days vs. 6.92¡¾1.87 days, P=0.618).
Conclusion: Early administration of steroids on patients with M. pneumoniae pneumonia reduced the duration of fever, but there was no difference in duration of admission and x-ray deterioration.
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KEYWORD
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Mycoplasma pneumonia, Steroid, Macrolide
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